In vitro studies, 25C-NBOMe is demonstrated to exhibit cytotoxicity on neuronal cell strains SH-SY5Y, PC12, and SN471, along with the compound was extra strong than methamphetamine at decreasing the visibility on the respective cells; the neurotoxicity in the compound entails activation of MAPK/ERK cascade and inhibition of Akt/PKB signaling pathway. https://psychonauthome.com/